Generalization of endothelial modelling of TSPO PET imaging: Considerations on tracer affinities

The 18 kDa translocator protein (TSPO) is a marker of microglia activation and the main target of positron emission tomography (PET) ligands for neuroinflammation. Previous works showed that accounting for TSPO endothelial binding improves PET quantification for [(11)C]PBR28, [(18)F]DPA714 and [(11)...

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Veröffentlicht in:J Cereb Blood Flow Metab
Hauptverfasser: Rizzo, Gaia, Veronese, Mattia, Tonietto, Matteo, Bodini, Benedetta, Stankoff, Bruno, Wimberley, Catriona, Lavisse, Sonia, Bottlaender, Michel, Bloomfield, Peter S, Howes, Oliver, Zanotti-Fregonara, Paolo, Turkheimer, Federico E, Bertoldo, Alessandra
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2017
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501510/
https://ncbi.nlm.nih.gov/pubmed/29135382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17742004
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