MLN4924 Exerts a Neuroprotective Effect against Oxidative Stress via Sirt1 in Spinal Cord Ischemia-Reperfusion Injury

Oxidative stress is a leading contributor to spinal cord ischemia-reperfusion (SCIR) injury. Recently, MLN4924, a potent and selective inhibitor of the NEDD8-activating enzyme, was shown to exert a neuroprotective effect against oxidative stress in vitro. However, it is unknown whether MLN4924 plays...

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Publicado en:Oxid Med Cell Longev
Autores principales: Yu, Sifei, Xie, Lei, Liu, Zhuochao, Li, Changwei, Liang, Yu
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501157/
https://ncbi.nlm.nih.gov/pubmed/31178972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7283639
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