Successful treatment with nivolumab for SMARCA4‐deficient non‐small cell lung carcinoma with a high tumor mutation burden: A case report

SMARCA4 is a subunit of the switch/sucrose non‐fermentable (SWI/SNF) chromatin‐remodeling complex. An effective treatment for SMARCA4‐deficient non‐small cell lung carcinoma (NSCLC) has not yet been established. Correlations between a response to immune checkpoint inhibitors and the SWI/SNF complex...

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Detalhes bibliográficos
Publicado no:Thorac Cancer
Main Authors: Naito, Tomoyuki, Umemura, Shigeki, Nakamura, Hiroshi, Zenke, Yoshitaka, Udagawa, Hibiki, Kirita, Keisuke, Matsumoto, Shingo, Yoh, Kiyotaka, Niho, Seiji, Motoi, Noriko, Aokage, Keijyu, Tsuboi, Masahiro, Ishii, Genichiro, Goto, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons Australia, Ltd 2019
Assuntos:
Case Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501032/
https://ncbi.nlm.nih.gov/pubmed/30972962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.13070
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