Synergistic interaction of gemcitabine and paclitaxel by modulating acetylation and polymerization of tubulin in non-small cell lung cancer cell lines

Background: The combination of gemcitabine (GEM) and paclitaxel (PTX) was appealing for clinical exploration due to different mechanisms of action and partially non-overlapping toxicities. Purpose: The aim of this study was to elucidate a potential effect of this combination on the proliferation of...

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Veröffentlicht in:Cancer Manag Res
Hauptverfasser: Effendi, Wiwin Is, Nagano, Tatsuya, Tachihara, Motoko, Umezawa, Kanoko, Kiriu, Tatsunori, Dokuni, Ryota, Katsurada, Masahiro, Yamamoto, Masatsugu, Kobayashi, Kazuyuki, Nishimura, Yoshihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2019
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500879/
https://ncbi.nlm.nih.gov/pubmed/31118789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S193789
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