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Roles of K(+) and Cation Channels in ORL-1 Receptor-mediated Depression of Neuronal Excitability and Epileptic Activities in the Medial Entorhinal Cortex

Nociceptin (NOP) is an endogenous opioid-like peptide that selectively activates the opioid receptor-like (ORL-1) receptors. The entorhinal cortex (EC) is closely related to temporal lobe epilepsy and expresses high densities of ORL-1 receptors. However, the functions of NOP in the EC, especially in...

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Publicat a:Neuropharmacology
Autors principals: Li, Huiming, Hu, Binqi, Zhang, Hao-peng, Boyle, Cody A., Lei, Saobo
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500758/
https://ncbi.nlm.nih.gov/pubmed/30998945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2019.04.017
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