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Dysregulated Chemokine Signaling in Cystic Fibrosis Lung Disease: A Potential Therapeutic Target

CF lung disease is characterized by a chronic and non-resolving activation of the innate immune system with excessive release of chemokines/cytokines including IL-8 and persistent infiltration of immune cells, mainly neutrophils, into the airways. Chronic infection and impaired immune response event...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Drug Targets
Hauptverfasser: Guan, Xiaoqing, Hou, Yuning, Sun, Fei, Yang, Zhe, Li, Chunying
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500735/
https://ncbi.nlm.nih.gov/pubmed/26648071
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