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Brain transcriptome analysis of a familial Alzheimer’s disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production

To prevent or ameliorate Alzheimer’s disease (AD) we must understand its molecular basis. AD develops over decades but detailed molecular analysis of AD brains is limited to postmortem tissue where the stresses initiating the disease may be obscured by compensatory responses and neurodegenerative pr...

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Publicat a:Mol Brain
Autors principals: Newman, Morgan, Hin, Nhi, Pederson, Stephen, Lardelli, Michael
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500017/
https://ncbi.nlm.nih.gov/pubmed/31053140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-019-0467-y
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