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STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism

Mitophagy is the selective autophagic targeting and removal of dysfunctional mitochondria. While PINK1/Parkin-dependent mitophagy is well-characterized, PINK1/Parkin-independent route is poorly understood. Using structure illumination microscopy (SR-SIM), we demonstrate that the SNARE protein Syntax...

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Publicat a:Nat Commun
Autors principals: Xian, Hongxu, Yang, Qiaoyun, Xiao, Lin, Shen, Han-Ming, Liou, Yih-Cherng
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499814/
https://ncbi.nlm.nih.gov/pubmed/31053718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10096-1
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