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Gene Variants in NKX2-1 Do Not Represent a Major Etiological Factor of Primary Congenital Hypothyroidism in Mexican Population

Congenital hypothyroidism (CH), attributable to thyroid dysgenesis (TD), has an unusually high prevalence in Mexican population but the causes are unknown. NKX2-1 , as a candidate gene, was subjected to automated Sanger sequencing in 122 unrelated Mexican patients with CH/TD. Although this study inc...

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Detalhes bibliográficos
Publicado no:J Pediatr Genet
Main Authors: González-del Angel, Ariadna, Fernández-Hernández, Liliana, Sánchez-Verdiguel, Iraís, González-Núñez, Aidy, Martínez-Cruz, Víctor, Sánchez, Carmen, Moreno-Rojas, Rosario, Alcántara-Ortigoza, Miguel Angel
Formato: Artigo
Idioma:Inglês
Publicado em: Georg Thieme Verlag KG 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499623/
https://ncbi.nlm.nih.gov/pubmed/31061744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0038-1676644
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