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T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells

Differentiation of naive CD4(+) T cells into IFN-γ-producing T helper 1 (T(H)1) cells is pivotal for protective immune responses against intracellular pathogens. T-bet, a recently discovered member of the T-box transcription factor family, has been reported to play a critical role in this process, p...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lighvani, Andre A., Frucht, David M., Jankovic, Dragana, Yamane, Hidehiro, Aliberti, Julio, Hissong, Bruce D., Nguyen, Bai V., Gadina, Massimo, Sher, Alan, Paul, William E., O'Shea, John J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2001
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64996/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11752460/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.261570598
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