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Genome-Wide Discovery of DEAD-Box RNA Helicase Targets Reveals RNA Structural Remodeling in Transcription Termination

RNA helicases are a class of enzymes that unwind RNA duplexes in vitro but whose cellular functions are largely enigmatic. Here, we provide evidence that the DEAD-box protein Dbp2 remodels RNA-protein complex (RNP) structure to facilitate efficient termination of transcription in Saccharomyces cerev...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genetics
Hauptverfasser: Lai, Yu-Hsuan, Choudhary, Krishna, Cloutier, Sara C., Xing, Zheng, Aviran, Sharon, Tran, Elizabeth J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499532/
https://ncbi.nlm.nih.gov/pubmed/30902808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302058
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