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Accurate analysis of genuine CRISPR editing events with ampliCan

We present ampliCan, an analysis tool for genome editing that unites highly precise quantification and visualization of genuine genome editing events. ampliCan features nuclease-optimized alignments, filtering of experimental artifacts, event-specific normalization, and off-target read detection and...

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Bibliografiske detaljer
Udgivet i:Genome Res
Main Authors: Labun, Kornel, Guo, Xiaoge, Chavez, Alejandro, Church, George, Gagnon, James A., Valen, Eivind
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499316/
https://ncbi.nlm.nih.gov/pubmed/30850374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.244293.118
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