The CXCR4-LASP1-eIF4F Axis Promotes Translation of Oncogenic Proteins in Triple-Negative Breast Cancer Cells

Triple-negative breast cancer (TNBC) remains clinically challenging as effective targeted therapies are lacking. In addition, patient mortality mainly results from the metastasized lesions. CXCR4 has been identified to be one of the major chemokine receptors involved in breast cancer metastasis. Pre...

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Detalles Bibliográficos
Publicado en:Front Oncol
Autores principales: Howard, Cory M., Bearss, Nicole, Subramaniyan, Boopathi, Tilley, Augustus, Sridharan, Sangita, Villa, Nancy, Fraser, Christopher S., Raman, Dayanidhi
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499106/
https://ncbi.nlm.nih.gov/pubmed/31106142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00284
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