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The importance of controlling transcription elongation at coding and non-coding RNA loci

Here we discuss current paradigms for how transcription initiation and elongation control are achieved in mammalian cells, and how they differ at protein-coding mRNA genes vs. non-coding RNA (ncRNA) loci. We present a model for the function of ncRNAs wherein the act of transcription is regulatory, r...

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Détails bibliographiques
Publié dans:Cold Spring Harb Symp Quant Biol
Auteurs principaux: Scruggs, Benjamin S., Adelman, Karen
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499063/
https://ncbi.nlm.nih.gov/pubmed/27325707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2015.80.027235
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