Comprehensive Evaluation of the Expressed CD8+ T Cell Epitope Space Using High-Throughput Epitope Mapping

T cell immunity is traditionally assessed through functional recall assays, which detect the consequences of the T cells' antigen encounter, or via fluorescently labeled multimers that selectively bind peptide-specific T cell receptors. Using either approach, if the wrong antigen or peptide of...

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Udgivet i:Front Immunol
Main Authors: Lehmann, Paul V., Suwansaard, Maneewan, Zhang, Ting, Roen, Diana R., Kirchenbaum, Greg A., Karulin, Alexey Y., Lehmann, Alexander, Reche, Pedro A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499037/
https://ncbi.nlm.nih.gov/pubmed/31105686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00655
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