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Battle of the sexes: contrasting roles of testis-specific protein Y-encoded (TSPY) and TSPX in human oncogenesis

The Y-located testis-specific protein Y-encoded (TSPY) and its X-homologue TSPX originated from the same ancestral gene, but act as a proto-oncogene and a tumor suppressor gene, respectively. TSPY has specialized in male-specific functions, while TSPX has assumed the functions of the ancestral gene....

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Bibliografski detalji
Izdano u:Asian J Androl
Glavni autori: Lau, Yun-Fai Chris, Li, Yunmin, Kido, Tatsuo
Format: Artigo
Jezik:Inglês
Izdano: Wolters Kluwer - Medknow 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498724/
https://ncbi.nlm.nih.gov/pubmed/29974883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/aja.aja_43_18
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