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Battle of the sexes: contrasting roles of testis-specific protein Y-encoded (TSPY) and TSPX in human oncogenesis

The Y-located testis-specific protein Y-encoded (TSPY) and its X-homologue TSPX originated from the same ancestral gene, but act as a proto-oncogene and a tumor suppressor gene, respectively. TSPY has specialized in male-specific functions, while TSPX has assumed the functions of the ancestral gene....

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Detalhes bibliográficos
Publicado no:Asian J Androl
Main Authors: Lau, Yun-Fai Chris, Li, Yunmin, Kido, Tatsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer - Medknow 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498724/
https://ncbi.nlm.nih.gov/pubmed/29974883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/aja.aja_43_18
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