Tristetraprolin specifically regulates the expression and alternative splicing of immune response genes in HeLa cells

BACKGROUND: Tristetraprolin (TTP) is an RNA binding protein that plays a critical role in regulating proinflammatory immune responses by destabilizing target mRNAs via binding to their AU-rich elements (AREs) in the 3′-UTRs of mRNAs. A recent CLIP-seq study revealed that TTP-binding sites are enrich...

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Dettagli Bibliografici
Pubblicato in:BMC Immunol
Autori principali: Tu, Yafang, Wu, Xiongfei, Yu, Fengyun, Dang, Jianzhong, Wang, Juan, Wei, Yaxun, Cai, Zhitao, Zhou, Zhipeng, Liao, Wenliang, Li, Lian, Zhang, Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498542/
https://ncbi.nlm.nih.gov/pubmed/31046669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-019-0292-1
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