A substitution in the pre-S1 promoter region is associated with the viral regulation of hepatitis B virus

BACKGROUND: Much evidence has demonstrated the influence of Hepatitis B virus (HBV) mutations on the clinical course of HBV infection. As large (L) protein plays a crucial role for viral entry, we hypothesized that mutations in the pre-S1 promoter region might affect the expression of L protein and...

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Dettagli Bibliografici
Pubblicato in:Virol J
Autori principali: Ogura, Suguru, Tameda, Masahiko, Sugimoto, Kazushi, Ikejiri, Makoto, Usui, Masanobu, Ito, Masaaki, Takei, Yoshiyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498540/
https://ncbi.nlm.nih.gov/pubmed/31046787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-019-1169-x
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