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The expression of human α-like globin genes in transgenic mice mediated by bacterial artificial chromosome

After screening a bacterial artificial chromosome of human genomic DNA library with human HS-40, ζ-, α-, and θ-globin probes, a 110-kb clone bearing the whole human α-globin gene cluster was obtained and rare restriction endonuclease mapping was performed. The bacterial artificial chromosome DNA was...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Feng, Dong-Xiao, Liu, De-Pei, Huang, Yue, Wu, Lin, Li, Tie-Chang, Wu, Min, Tang, Xiao-Bin, Liang, Chih-Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64985/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11742079/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.251550598
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