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Haemophagocytic lymphohistiocytosis in patients treated with immune checkpoint inhibitors: analysis of WHO global database of individual case safety reports

BACKGROUND: Immune checkpoint inhibitor (ICI) use in clinical practice has unravelled a spectrum of immune-related adverse events (irAEs) due to immune system hyper-activation. ICI-related haemophagocytic lymphohistiocytosis (HLH) has been recently outlined in single case reports, raising a concern...

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Bibliographische Detailangaben
Veröffentlicht in:J Immunother Cancer
Hauptverfasser: Noseda, Roberta, Bertoli, Raffaela, Müller, Laura, Ceschi, Alessandro
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498487/
https://ncbi.nlm.nih.gov/pubmed/31046841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0598-9
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