A Pertussis Outer Membrane Vesicle-Based Vaccine Induces Lung-Resident Memory CD4 T Cells and Protection Against Bordetella pertussis, Including Pertactin Deficient Strains

Pertussis is a respiratory infectious disease that has been resurged during the last decades. The change from the traditional multi-antigen whole-cell pertussis (wP) vaccines to acellular pertussis (aP) vaccines that consist of a few antigens formulated with alum, appears to be a key factor in the r...

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Bibliographic Details
Published in:Front Cell Infect Microbiol
Main Authors: Zurita, María Eugenia, Wilk, Mieszko M., Carriquiriborde, Francisco, Bartel, Erika, Moreno, Griselda, Misiak, Alicja, Mills, Kingston H. G., Hozbor, Daniela
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Cellular and Infection Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498398/
https://ncbi.nlm.nih.gov/pubmed/31106160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00125
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