Marked improvement in leptomeningeal carcinomatosis and spinal cord metastases following alectinib treatment of crizotinib-resistant, ALK-positive lung adenocarcinoma

We report a case of 50-year-old Japanese female with anaplastic lymphoma kinase (ALK)-positive, crizotinib-resistant lung adenocarcinoma, whose leptomeningeal carcinomatosis and spinal cord metastases were dramatically improved by the second-generation ALK inhibitor alectinib. Magnetic resonance ima...

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Bibliographic Details
Published in:Int Cancer Conf J
Main Authors: Kuribayashi, Hidehiko, Abe, Shinji, Kuse, Naoyuki, Kusunoki, Yuji, Narato, Ritsuko, Saito, Hitoshi, Gemma, Akihiko
Format: Artigo
Language:Inglês
Published: Springer Japan 2015
Subjects:
Case Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498346/
https://ncbi.nlm.nih.gov/pubmed/31149429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13691-015-0231-9
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