Identification of the OXA-48 Carbapenemase Family by Use of Tryptic Peptides and Liquid Chromatography-Tandem Mass Spectrometry

Phenotypic detection of the OXA-48-type class D β-lactamases in Enterobacteriaceae is challenging. We describe a rapid (less than 90 min) assay for the identification of OXA-48 family carbapenemases in subcultured bacterial isolates based on a genoproteomic approach. Following in silico trypsin dige...

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Udgivet i:J Clin Microbiol
Main Authors: Strich, Jeffrey R., Wang, Honghui, Cissé, Ousmane H., Youn, Jung-Ho, Drake, Steven K., Chen, Yong, Rosenberg, Avi Z., Gucek, Marjan, McGann, Patrick T., Dekker, John P., Suffredini, Anthony F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Bacteriology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498012/
https://ncbi.nlm.nih.gov/pubmed/30814261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01240-18
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