Receptor-destroying enzyme (RDE) from Vibrio cholerae modulates IgE activity and reduces the initiation of anaphylaxis

IgE plays a key role in allergies by binding to allergens and then sensitizing mast cells through the Fc receptor, resulting in the secretion of proinflammatory mediators. Therefore, IgE is a major target for managing allergies. Previous studies have reported that oligomannose on IgE can be a potent...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Yamazaki, Tatsuya, Inui, Masanori, Hiemori, Keiko, Tomono, Susumu, Itoh, Makoto, Ichimonji, Isao, Nakashima, Akina, Takagi, Hidekazu, Biswas, Mrityunjoy, Izawa, Kumi, Kitaura, Jiro, Imai, Teruko, Sugiura, Nobuo, Tateno, Hiroaki, Akashi-Takamura, Sachiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2019
Onderwerpen:
Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497938/
https://ncbi.nlm.nih.gov/pubmed/30833330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006375
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