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microRNA-944 inhibits the malignancy of hepatocellular carcinoma by directly targeting IGF-1R and deactivating the PI3K/Akt signaling pathway

Purpose: Recent studies have identified microRNA-944 (miR-944) as a cancer-related miRNA, but its expression and precise functions in hepatocellular carcinoma (HCC) remain unknown. Patients and methods: miR-944 expression in HCC tissues and cell lines were detected by RT-qPCR. A series of functional...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Manag Res
Hauptverfasser: Lv, Lili, Wang, Xiaodong, Ma, Tonghui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497845/
https://ncbi.nlm.nih.gov/pubmed/31114322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S199818
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