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Enzyme-responsive mesoporous silica nanoparticles for tumor cells and mitochondria multistage-targeted drug delivery

Background: Drug delivery systems (DDS) capable of targeting both cell and organelle levels are highly desirable for effective cancer therapy. In this study, we developed a novel enzyme-responsive, multistage-targeted anticancer DDS based on mesoporous silica nanoparticles (MSNs), which possessed bo...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Naz, Safia, Wang, Mingyu, Han, Yuning, Hu, Bin, Teng, Liping, Zhou, Juan, Zhang, Huijie, Chen, Jinghua
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497824/
https://ncbi.nlm.nih.gov/pubmed/31114189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S202210
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