Checkpoint blockade and nanosonosensitizer-augmented noninvasive sonodynamic therapy combination reduces tumour growth and metastases in mice

Combined checkpoint blockade (e.g., PD1/PD-L1) with traditional clinical therapies can be hampered by side effects and low tumour-therapeutic outcome, hindering broad clinical translation. Here we report a combined tumour-therapeutic modality based on integrating nanosonosensitizers-augmented noninv...

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Pubblicato in:Nat Commun
Autori principali: Yue, Wenwen, Chen, Liang, Yu, Luodan, Zhou, Bangguo, Yin, Haohao, Ren, Weiwei, Liu, Chang, Guo, Lehang, Zhang, Yifeng, Sun, Liping, Zhang, Kun, Xu, Huixiong, Chen, Yu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497709/
https://ncbi.nlm.nih.gov/pubmed/31048681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09760-3
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