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Inhibition of the NLRP3 inflammasome can prevent sterile intra-amniotic inflammation, preterm labor/birth, and adverse neonatal outcomes

Sterile intra-amniotic inflammation is commonly observed in patients with spontaneous preterm labor, a syndrome that commonly precedes preterm birth, the leading cause of perinatal morbidity and mortality worldwide. However, the mechanisms leading to sterile intra-amniotic inflammation are poorly un...

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Bibliografiske detaljer
Udgivet i:Biol Reprod
Main Authors: Gomez-Lopez, Nardhy, Romero, Roberto, Garcia-Flores, Valeria, Leng, Yaozhu, Miller, Derek, Hassan, Sonia S, Hsu, Chaur-Dong, Panaitescu, Bogdan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497524/
https://ncbi.nlm.nih.gov/pubmed/30596885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioy264
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