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Plasma RANKL levels are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

BACKGROUND: Aberrant progesterone/receptor activator of nuclear factor κβ (RANK) signaling has been implicated in BRCA1 breast cancer development. Furthermore, lower circulating RANKL has been reported among women with a BRCA mutation compared to non-carriers; however, there have been no reports of...

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Publicat a:Oncotarget
Autors principals: Zaman, Tasnim, Sun, Ping, Narod, Steven A., Salmena, Leonardo, Kotsopoulos, Joanne
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497430/
https://ncbi.nlm.nih.gov/pubmed/31069010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26810
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