Dengue virus nonstructural protein 1 activates platelets via Toll-like receptor 4, leading to thrombocytopenia and hemorrhage

Dengue virus (DENV) infection, the most common mosquito-transmitted viral infection, can cause a range of diseases from self-limiting dengue fever to life-threatening dengue hemorrhagic fever and shock syndrome. Thrombocytopenia is a major characteristic observed in both mild and severe dengue disea...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Chao, Chiao-Hsuan, Wu, Wei-Chueh, Lai, Yen-Chung, Tsai, Pei-Jane, Perng, Guey-Chuen, Lin, Yee-Shin, Yeh, Trai-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497319/
https://ncbi.nlm.nih.gov/pubmed/31009511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007625
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