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RHOA activity in expanding blastocysts is essential to regulate HIPPO-YAP signaling and to maintain the trophectoderm-specific gene expression program in a ROCK/actin filament-independent manner
STUDY QUESTION: What molecular signals are required to maintain the functional trophectoderm (TE) during blastocyst expansion of the late stage of preimplantation development? SUMMARY ANSWER: The activity of ras homology family member A (RHOA) GTPases is necessary to retain the expanded blastocyst c...
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| Veröffentlicht in: | Mol Hum Reprod |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6497036/ https://ncbi.nlm.nih.gov/pubmed/30395288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gay048 |
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