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The Wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis

Wnt proteins can activate different intracellular signaling pathways. These pathways need to be tightly regulated for proper cardiogenesis. The canonical Wnt/β-catenin inhibitor Dkk1 has been shown to be sufficient to trigger cardiogenesis in gain-of-function experiments performed in multiple model...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Guo, Yanchun, Dorn, Tatjana, Kühl, Susanne J., Linnemann, Alexander, Rothe, Melanie, Pfister, Astrid S., Vainio, Seppo, Laugwitz, Karl-Ludwig, Moretti, Alessandra, Kühl, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496975/
https://ncbi.nlm.nih.gov/pubmed/30797757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2019.02.009
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