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Untangling knots between autophagic targets and candidate drugs, in cancer therapy
Autophagy is an evolutionarily conserved lysosomal mechanism implicated in a wide variety of pathological processes, such as cancer. Autophagy can be regulated by a limited number of autophagy‐related genes (Atgs) such as oncogenic Bcl‐2/Bcl‐X (L), mTORC1, Akt and PI3KCI, and tumour suppressive prot...
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| Publicado no: | Cell Prolif |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6496907/ https://ncbi.nlm.nih.gov/pubmed/25650136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12167 |
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