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Sevoflurane represses the self‐renewal ability by regulating miR‐7a,7b/Klf4 signalling pathway in mouse embryonic stem cells

Sevoflurane is a frequently‐used clinical inhalational anaesthetic and can cause toxicity to embryos during foetal development. Embryonic stem cells (ESCs) are derived from the inner cell mass of blastospheres and can be used as a useful model of early development. Here, we found that sevoflurane si...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Wang, Qimin, Li, Guifeng, Li, Baolin, Chen, Qiu, Lv, Dongdong, Liu, Jiaying, Ma, Jieyu, Sun, Nai, Yang, Longqiu, Fei, Xuejie, Song, Qiong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496746/
https://ncbi.nlm.nih.gov/pubmed/27535693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12283
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