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Rapamycin inhibits acrolein‐induced apoptosis by alleviating ROS‐driven mitochondrial dysfunction in male germ cells

OBJECTIVES: Acrolein (Acr) is a highly reactive α, β‐unsaturated aldehyde, which can induce reactive oxygen species (ROS) generation. Several factors, including lipid peroxidation, clinical use of cyclophosphamide, fried foods, automobile exhausts, smoking and aging can increase its concentration in...

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Detalles Bibliográficos
Publicado en:Cell Prolif
Main Authors: He, X., Song, W., Liu, C., Chen, S., Hua, J.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496251/
https://ncbi.nlm.nih.gov/pubmed/24483236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12091
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