Lipid peroxide‐induced redox imbalance differentially mediates CaCo‐2 cell proliferation and growth arrest

Abstract. Dietary oxidants like lipid hydroperoxides (LOOH) can perturb cellular glutathione/glutathione disulphide (GSH/GSSG) status and disrupt mucosal turnover. This study examines the effect of LOOH on GSH/GSSG balance and phase transitions in the human colon cancer CaCo‐2 cell. LOOH at 1 or 5 µ...

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Publicat a:Cell Prolif
Autors principals: Gotoh, Yudai, Noda, Takahiro, Iwakiri, Ryuichi, Fujimoto, Kazuma, Rhoads, Carol A., Aw, Tak Yee
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Ltd 2002
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496176/
https://ncbi.nlm.nih.gov/pubmed/12153614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2184.2002.00241.x
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