Revising Pediatric Vancomycin Dosing Accounting for Nephrotoxicity in a Pharmacokinetic-Pharmacodynamic Model

This study aimed to suggest an initial pediatric vancomycin dose regimen through population pharmacokinetic-pharmacodynamic modeling. A population pharmacokinetic approach was used to analyze vancomycin concentration-time data from a large pediatric cohort. Pharmacokinetic target attainment for pati...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Kloprogge, Frank, Hill, Louise F., Booth, John, Klein, Nigel, Irwin, Adam D., Dixon, Garth, Standing, Joseph F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496060/
https://ncbi.nlm.nih.gov/pubmed/30833429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00067-19
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