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Effects of 5‐fluorouracil on cell cycle arrest and toxicity induced by X‐irradiation in normal mammalian cells

ABSTRACT. From clinical studies in cancer patients and experimental in vitro studies, there is evidence of an increased cytotoxic effect, and even synergy, when irradiation is combined with 5‐fluorouracil (5‐FU). The mechanism for this is unclear. MATERIALS AND METHODS: Mouse fetuses (C(3)H) have be...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Nylén, U., Cekan, E., Jonasson, G.‐B., Lewin, F., Skog, S.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Ltd 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495968/
https://ncbi.nlm.nih.gov/pubmed/11348424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2184.2001.00200.x
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