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p53 functional assays: detecting p53 mutations in both the germline and in sporadic tumours

The tumour suppressor gene p53 is the gene most often reported to be mutated in clinical cancers with something like half of all tumours harbouring mutations. Further, many studies have suggested that p53 mutations have prognostic importance and sometimes are a significant factor in determining the...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Camplejohn, R.S., Rutherford, J.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Ltd 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495849/
https://ncbi.nlm.nih.gov/pubmed/11284915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2184.2001.00193.x
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