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γ‐Tocotrienol reversal of epithelial‐to‐mesenchymal transition in human breast cancer cells is associated with inhibition of canonical Wnt signalling

OBJECTIVES: Frizzled‐7 (FZD7) receptor‐dependent activation of the canonical Wnt/β‐catenin pathway plays a crucial role in epithelial‐to‐mesenchymal transition (EMT) and breast cancer metastasis. FZD7 and its co‐receptor, low‐density lipoprotein receptor‐related protein 6 (LRP6), are highly expresse...

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Publicat a:Cell Prolif
Autors principals: Ahmed, R. A., Alawin, O. A., Sylvester, P. W.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495554/
https://ncbi.nlm.nih.gov/pubmed/27323693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12270
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