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Reduced glucocorticoid receptors: consequence or cause of depression?

Dysfunction of the hypothalamic–pituitary–adrenal (HPA) axis is common in patients with major depression. A recent study demonstrates that reduced expression of the glucocorticoid receptor in mice causes depression-like behaviors and HPA axis dysfunction following stressor exposure. This model offer...

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書目詳細資料
發表在:Trends Endocrinol Metab
Main Authors: Neigh, Gretchen N., Nemeroff, Charles B.
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495542/
https://ncbi.nlm.nih.gov/pubmed/16574425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2006.03.002
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