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Reduced glucocorticoid receptors: consequence or cause of depression?
Dysfunction of the hypothalamic–pituitary–adrenal (HPA) axis is common in patients with major depression. A recent study demonstrates that reduced expression of the glucocorticoid receptor in mice causes depression-like behaviors and HPA axis dysfunction following stressor exposure. This model offer...
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| Publié dans: | Trends Endocrinol Metab |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6495542/ https://ncbi.nlm.nih.gov/pubmed/16574425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2006.03.002 |
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