Quercetin induces cytochrome‐c release and ROS accumulation to promote apoptosis and arrest the cell cycle in G2/M, in cervical carcinoma: signal cascade and drug‐DNA interaction

OBJECTIVES: Small aromatic compounds like flavonoids can intercalate with DNA molecules bringing about conformational changes leading to reduced replication and transcription. Here, we have examined one dietary flavonoid, quercetin (found in many fruit and vegetables), for possible anti‐cancer effec...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Bishayee, K., Ghosh, S., Mukherjee, A., Sadhukhan, R., Mondal, J., Khuda‐Bukhsh, A. R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495502/
https://ncbi.nlm.nih.gov/pubmed/23510470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12017
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