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Binding of Staphylococcus aureus Protein A to von Willebrand Factor Is Regulated by Mechanical Force

Binding of Staphylococcus aureus to the large plasma glycoprotein von Willebrand factor (vWF) is controlled by hydrodynamic flow conditions. Currently, we know little about the molecular details of this shear-stress-dependent interaction. Using single-molecule atomic force microscopy, we demonstrate...

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Publicat a:mBio
Autors principals: Viela, Felipe, Prystopiuk, Valeria, Leprince, Audrey, Mahillon, Jacques, Speziale, Pietro, Pietrocola, Giampiero, Dufrêne, Yves F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495375/
https://ncbi.nlm.nih.gov/pubmed/31040240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00555-19
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