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Protein Aggregation Capture on Microparticles Enables Multipurpose Proteomics Sample Preparation
Universal proteomics sample preparation is challenging because of the high heterogeneity of biological samples. Here we describe a novel mechanism that exploits the inherent instability of denatured proteins for nonspecific immobilization on microparticles by protein aggregation capture. To demonstr...
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| Udgivet i: | Mol Cell Proteomics |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Biochemistry and Molecular Biology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6495262/ https://ncbi.nlm.nih.gov/pubmed/30833379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR118.001270 |
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