AMP-activated protein kinase activation ameliorates eicosanoid dysregulation in high-fat-induced kidney disease in mice

High-fat diet (HFD) causes renal lipotoxicity that is ameliorated with AMP-activated protein kinase (AMPK) activation. Although bioactive eicosanoids increase with HFD and are essential in regulation of renal disease, their role in the inflammatory response to HFD-induced kidney disease and their mo...

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Bibliographic Details
Published in:J Lipid Res
Main Authors: Declèves, Anne-Emilie, Mathew, Anna V., Armando, Aaron M., Han, Xianlin, Dennis, Edward A., Quehenberger, Oswald, Sharma, Kumar
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2019
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495162/
https://ncbi.nlm.nih.gov/pubmed/30862696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M088690
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