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The Rabl configuration limits topological entanglement of chromosomes in budding yeast

The three dimensional organization of genomes remains mostly unknown due to their high degree of condensation. Biophysical studies predict that condensation promotes the topological entanglement of chromatin fibers and the inhibition of function. How organisms balance between functionally active gen...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pouokam, Maxime, Cruz, Brian, Burgess, Sean, Segal, Mark R., Vazquez, Mariel, Arsuaga, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494875/
https://ncbi.nlm.nih.gov/pubmed/31043625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42967-4
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