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Drug-like Fragments Inhibit agr-Mediated Virulence Expression in Staphylococcus aureus

In response to the increasingly problematic emergence of antibiotic resistance, novel strategies for combating pathogenic bacteria are being investigated. Targeting the agr quorum sensing system, which regulates expression of virulence in Staphylococcus aureus, is one potentially useful approach for...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bezar, Ian F., Mashruwala, Ameya A., Boyd, Jeffrey M., Stock, Ann M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494831/
https://ncbi.nlm.nih.gov/pubmed/31043623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42853-z
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