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Mouse models and strain-dependency of Chédiak-Higashi syndrome-associated neurologic dysfunction
Chédiak-Higashi syndrome (CHS) is a lethal disorder caused by mutations in the LYST gene that involves progressive neurologic dysfunction. Lyst-mutant mice exhibit neurologic phenotypes that are sensitive to genetic background. On the DBA/2J-, but not on the C57BL/6J-background, Lyst-mutant mice exh...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6494809/ https://ncbi.nlm.nih.gov/pubmed/31043676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42159-0 |
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