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Synthesis, Structural Reassignment, and Antibacterial Evaluation of 2,18-Seco-Lankacidinol B

Lankacidins are a group of polyketide natural products with activity against several strains of Gram-positive bacteria. We developed a route to stereochemically diverse variants of 2,18-seco-lankacidinol B and found that the stereochemical assignment at C4 requires revision. This has interesting imp...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Yao, Yanmin, Cai, Lingchao, Seiple, Ian B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494672/
https://ncbi.nlm.nih.gov/pubmed/30133094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201808612
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