Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets

Bone marrow megakaryocytes engulf neutrophils in a phenomenon termed emperipolesis. We show here that emperipolesis is a dynamic process mediated actively by both lineages, in part through the β2-integrin/ICAM-1/ezrin pathway. Tethered neutrophils enter in membrane-bound vesicles before penetrating...

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Vydáno v:eLife
Hlavní autoři: Cunin, Pierre, Bouslama, Rim, Machlus, Kellie R, Martínez-Bonet, Marta, Lee, Pui Y, Wactor, Alexandra, Nelson-Maney, Nathan, Morris, Allyn, Guo, Li, Weyrich, Andrew, Sola-Visner, Martha, Boilard, Eric, Italiano, Joseph E, Nigrovic, Peter A
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494422/
https://ncbi.nlm.nih.gov/pubmed/31042146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44031
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